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GeDaC Newsletter - April 2025

· 2 min read

Dear CSI Researchers,​

We are excited to bring you the April edition of our monthly newsletter dedicated to keeping the CSI research community updated on the latest in bioinformatics and computational biology.

CSI x AWS Office Hours 🤝​

Cloudflow

We’re in the process of organizing an office hours collaboration between CSI Labs and AWS. As our needs for storage and compute resources continue to grow, it’s the perfect time to engage with one of the world’s leading cloud providers for expert guidance and insights.

To help us shape these sessions effectively, we’d appreciate your input. Your feedback will be instrumental in tailoring the agenda for this collaboration.

Survey Link

New Tools and Software Updates 🧰​

Dorado Update 🚀​

Oxford Nanopore's basecalling software has received a recent update, bringing speed improvements to high accuracy (HAC) and super accurate (SUP) basecalling models. For those of you interested in genome assembly, you will also enjoy speed improvements for read denoising and assembly. The update also offers accuracy improvements for polyA-tail estimation.

  • More information: Available on GitHub

SG-Nex long-read data release 🧬​

Long-read data and analysis from the Singapore Nanopore Expression Project (SG-Nex) was recently published. The repository includes data sequenced from seven human cell lines using three different library prep methods (dRNA, dcDNA, and cDNA). The raw and processed data from the study are publicly available online and free to download.

  • Data Release: Available on AWS
  • Data access tutorial: Learn more on GitHub
  • Research details: Manuscript available in Nature Methods

GeDaC Resource updates​

Facility Website Updates​

We're pleased to announce that we've updated our GeDaC website with improved navigation, new resource pages, and enhanced documentation. These changes make it easier for you to find the information and tools you need for your research.

CloudFlow Platform​

Our CloudFlow platform continues to provide CSI researchers with access to best-practice bioinformatics pipelines in the cloud. Remember that our team is available to assist with your computational needs and pipeline implementations.

Best regards,
GeDaC Team, CSI - NUS
📧 support@gedac.org
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